Our Research Insights
Can TMS help with dementia? The latest research in 2026
TMS is being studied for Alzheimer’s and mild cognitive impairment, with some encouraging results. An honest look at the brain targets, the treatment schedules, why age changes the dose, and what TMS can and cannot do. Estimated read time: about 11 minutes.
What is D-cycloserine and why do we use it in our One-Day Intensive?
What is D-cycloserine and why do we use it in our One-Day Intensive? If you’ve read about our One-Day Intensive, you’ve seen D-cycloserine (TMS 1-Day treatment suppliment) mentioned as part of the protocol. Most patients have never heard of it. The name sounds clinical. It sounds like a medication and the question of whether you’re being given an additional psychiatric drug during an already unfamiliar procedure is a reasonable thing to want answered clearly. Here’s the clear answer: D-cycloserine is not a psychiatric drug. It doesn’t alter your mood, your perception, or your cognition in any meaningful way at the
The THREE-D Trial – iTBS Non-Inferior to Standard rTMS for Depression (Blumberger et al. 2018)
The THREE-D Trial – iTBS Non-Inferior to Standard rTMS for Depression (Blumberger et al. 2018) What this study was Who was studied What the protocol involved What the results showed What it means and what it doesn’t Why this study matters for patients What this study was The THREE-D trial is the largest randomized controlled trial comparing intermittent theta burst stimulation to standard high-frequency rTMS for major depressive disorder. It was a non-inferiority trial, meaning its primary question was not whether iTBS was better than rTMS, but whether it was at least as good. It was conducted across multiple Canadian
What to expect during and after TMS – a realistic timeline from your first session to six weeks out
What to expect during and after TMS – a realistic timeline from your first session to six weeks out One of the most common reasons patients feel discouraged after starting TMS is a mismatch between what they expected and what actually happens. They finish their protocol, go home, and feel essentially the same as they did when they walked in. They conclude that TMS didn’t work. Often, it’s working. It just hasn’t finished yet. This article is our attempt to give you the most honest, complete picture of what TMS treatment actually looks like, from the day you arrive to
The ONE-D Study — One-Day Theta Burst Stimulation for Treatment-Resistant Depression (Vaughn et al., 2025)
The ONE-D Study — One-Day Theta Burst Stimulation for Treatment-Resistant Depression (Vaughn et al., 2025) What this study was Who was studied What the protocol involved What the results showed What it means — and what it doesn’t Why this study matters for patients What this study was The ONE-D study is the first published clinical trial evaluating a complete course of accelerated iTBS delivered in a single day, augmented with D-cycloserine to enhance neuroplasticity throughout treatment. It was conducted at the University of Toronto and affiliated sites under the direction of researchers including Dr. Jonathan Downar, one of the
Does insurance cover TMS?
Does insurance cover TMS? If you’re researching TMS and wondering whether your insurance will cover it, the short answer is: probably yes for traditional six-week TMS, for depression, if you meet your plan’s criteria. But insurance coverage for TMS is more complicated than that one-sentence answer suggests. And for many patients, the “covered” option turns out to be less financially straightforward and meaningfully less effective than the cash-pay accelerated alternatives. This article is going to walk through all of it honestly, including the math most clinic websites don’t show you. What insurance actually cares about The “Six-Week” barrier The math