D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation for Major Depressive Disorder (Cole, Sohn et al., 2022)
This was a randomized, double-blind, placebo-controlled clinical trial evaluating whether D-cycloserine improves the antidepressant effects of intermittent theta burst stimulation when administered im... ...more
Research Insights
June 09, 2026•3 min read
The THREE-D Trial - iTBS Non-Inferior to Standard rTMS for Depression (Blumberger et al. 2018)
The THREE-D trial is the largest randomized controlled trial comparing intermittent theta burst stimulation to standard high-frequency rTMS for major depressive disorder. ...more
Research Insights
June 08, 2026•3 min read
The ONE-D Study — One-Day Theta Burst Stimulation for Treatment-Resistant Depression (Vaughn et al., 2025)
The ONE-D study is the first published clinical trial evaluating a complete course of accelerated iTBS delivered in a single day, augmented with D-cycloserine to enhance neuroplasticity throughout tre... ...more
Research Insights
June 08, 2026•3 min read
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