What is D-cycloserine and why do we use it in our One-Day Intensive?
What is D-cycloserine and why do we use it in our One-Day Intensive? If you’ve read about our One-Day Intensive, you’ve seen D-cycloserine mentioned as part of the protocol. Most patients have never heard of it. The name sounds clinical. It sounds like a medication and the question of whether you’re being given an additional […]
The THREE-D Trial – iTBS Non-Inferior to Standard rTMS for Depression (Blumberger et al. 2018)
The THREE-D Trial – iTBS Non-Inferior to Standard rTMS for Depression (Blumberger et al. 2018) What this study was Who was studied What the protocol involved What the results showed What it means and what it doesn’t Why this study matters for patients What this study was The THREE-D trial is the largest randomized controlled […]
What to expect during and after TMS – a realistic timeline from your first session to six weeks out
What to expect during and after TMS – a realistic timeline from your first session to six weeks out One of the most common reasons patients feel discouraged after starting TMS is a mismatch between what they expected and what actually happens. They finish their protocol, go home, and feel essentially the same as they […]
The ONE-D Study — One-Day Theta Burst Stimulation for Treatment-Resistant Depression (Vaughn et al., 2025)
The ONE-D Study — One-Day Theta Burst Stimulation for Treatment-Resistant Depression (Vaughn et al., 2025) What this study was Who was studied What the protocol involved What the results showed What it means — and what it doesn’t Why this study matters for patients What this study was The ONE-D study is the first published […]
Does insurance cover TMS?
Does insurance cover TMS? If you’re researching TMS and wondering whether your insurance will cover it, the short answer is: probably yes for traditional six-week TMS, for depression, if you meet your plan’s criteria. But insurance coverage for TMS is more complicated than that one-sentence answer suggests. And for many patients, the “covered” option turns […]
Your brain can change. Here’s what that actually means.
Your brain can change. Here’s what that actually means. For decades, we assumed the adult brain was essentially fixed. You were born with a certain number of neurons, they wired themselves up during childhood and adolescence, and after that the structure was largely set. Mental illness, under this framework, was a malfunction in a static […]
What the SAINT Protocol Actually Showed… and What It Didn’t

What the SAINT Protocol Actually Showed… and What It Didn’t In 2022, a paper published in JAMA Psychiatry reported something that hadn’t been seen before in the treatment of depression: a 78.6% remission rate in patients with treatment-resistant major depressive disorder, achieved in five days. For context, patients with treatment-resistant depression are the hardest population […]